I used Profender spot on worm treatment on my Siamese cat two weeks ago and he's had diarrhea ever since. I have not changed his food and he's not prone to diarrhea he's a very robust seven year old. Everytime he goes on the litter tray it's diarrhea and he is distressed by it. I will not give it to him again I hope the diarrhea clears up soon he is still eating and drinking.

I am not a fan of keep dosing the cats with various treatments. Profender burned the back of my elderly cats neck and the hair fell out. Vet just says bring him back, for a fee of course, cat was to sore to be pulled around.

I used a different vet for my 2 year old, strictly indoor, cat. Other vet always had me bring a fecal sample. This one did not. They automatically gave him topical dewormer "just in case". About 4 hours after application, he began drooling excessively, eyes watering, running around the house and twitching. He would go hide for awhile until it happened again...he did this on and off for 24 hours and did not start acting like himself for 48 hours. He wasn't completely alright for about a week. Scared me to death! I wiped his back with wet washcloth, soap and water to try to remove any excess. DO NOT let vet use this on your cats!!!

Never again using this product that burns and hurts animals . Why would a vet be able to use this. This product should never be on the market. It is horrible.

A vet used this on my cat months ago, but I swear he does not seem like the same cat anymore. I think this has caused long-term side effects on him. New vet thinks it's his liver and pancreas. I am forking out money for an ultrasound now to see whats wrong. I am devastated. If I would have known, I would have asked for the pill form to administer myself in a pill pocket. He struggled to pill him, so thats why he used the profender. Do not use this!! See another vet if you have to and get milbemax instead.

My cat was lethargic for days, had a fever, and would barely eat. He still seems lethargic off and on after eating ever since.

My 7mnth old kitty had tapeworm. Vet gave him profender on back, she said it worked better than other meds. The next 3 days my cat did not eat or drink, became neurologic in his hind legs, can not jump, had 106 degree fever. My vet said in all his 10 years he's never seen a reaction to dewormer. He said that it's probably PIF that my kitty has. After looking at reviews and given the timing, I think not. My kitty may not make it and is at best overnight.

My beautiful 11 1/2 yr old Winnie is deathly sick after an application of pro fender. Within 24 hrs, she stopped eating, drinking, copious amounts of drool, already losing weight. Been to emergency vet once and heading to her vet in the a.m. This poison should be taken off the market. I only pray that my girl makes it. I have read the statistics on this medication and to say 1 cat died is certainly an understatement. I have read of several on this website alone. Absolutely do not use this product unless you want to risk losing your beloved pet.

I gave this to my 6 month old and he completely lost his appetite and energy. Its been 24 hrs and he still wont eat without help. He went from running around and constantly yelling especially around meal times to sleeping all day and barely making a peep. I never thought id miss hearing his yelling so much. Profender is poison im just glad his reaction hasnt been as severe as other cats. I got this from the vet and I thought I could trust it but apparently they dont care.

I use this in conjunction with Advocate as not all products treat every single parasite. Advocate doesn't treat tapeworm, but Profender does. Haven't had any issues with Profender in the few years I've been using it on six cats. Every animal is different though.

2 hours after careful application to our cat she began drooling and could not stand up properly, she had violent tremors and deteriorated rapidly. Rushed to the vets and they placed her in an oxygen tank and straight on IV fluids. Avoid this poison if you can.

I gave my 9 year old female house cat Profender prescribed by my vet because she had fleas and could have worms. She hasn't been the same since and it's nearly two weeks now. She's lethargic and looks depressed. She seems uncomfortable. I've taken back to the vet twice. The first time she had a very high temperature, over 40 degrees. The vet treated her with antibiotics and anti inflammatory. Also lactulose as she seems constipated although she's hardly eating anything. She's always been a lovable affectionate cat but now seems distant and disinterested. I'm really worried about her after reading the stories on this site.

The female has a large bald spot on the back of her neck where the medicine was applied. The male is lethargic and in some pain but this could be a result of the vaccines as well. The large dose Profender was applied by the vet three days ago. I do believe in routine de-worming but I am concerned. I feel the vet should have warned me of the possible side effects.

Right after applying this to my cats neck (between shoulder blades) she started running around acting crazy. I thought it was just because I had put medicine on her neck. Shortly after, she was drooling and gagging and constantly licking like something was in her mouth. She was acting aggressive toward our other cat and started looking like she felt really bad. After having it on about 15 minutes she was just getting worse so I put her in the bath tub and washed it off. Luckily she seems to be back to normal after bathing her. The vet recently used this on my other cat and he did fine but I definitely won’t be using this again.

Vet suggested a preventative deworming. It’s 3 AM and my two playful cats are now very sick. All balled up, not moving. Unresponsive. Been trying to wash this stuff off using dawn for dishes. Will contact different vet in AM to see what needs to be done to reverse the effects. Do not use! This stuff is pure poison.

Like many others I read the reviews after I had used it. Glad I did or I may not have bought it. After years of torture to the cat and myself trying to force tablets down his firmly clenched jaws ... We will suffer no more. He was fine with application, was happy ( as happy as old cats can be) after and apart from a restless belly, 24 hrs on, he is his normal whiny, self centered, slightly crazy, ignorant self. Definitely recommend to those who have awkward cats.

Within 12 hours of first administering to our younger cat, he started having severe seizures, completely unresponsive, appears near death, we put it right between shoulder blades so he couldn't have ingested it. Obviously having a reaction to it because he has not taken any other meds and no other lifestyle changes.

I bought this treatment from my vet and applied it to the back of my cats neck. He ran off terrified and all his fur on the back of his neck has fallen out. He looks terrible. I washed it off. I feel bad for using this. Never again.